The most important of the Portuguese paintings is, without doubt, the polyptych from St Vincent's altar, which was found in the Sao Vicente de Fora monastery and restored in 1910. Uncertainty has surrounded the origins of the "Adoration of St Vincent" ("Veneraçao a Sao Vicente"). Both the exact date of the work and the artist have not been clearly identified until now. It is generally accepted that Nuno Gonçalves, who was Afonso V's court artist from 1450 to 1467, painted this six-part altarpiece. The work is held to be an important historico-cultural document, as some prominent personalities from 15th C. Portuguese society are depicted on it. However, art historians are not always agreed on the identity of the people portrayed. A total of 60 people can be seen, including the most important from the age of Portugal's voyages of discovery. Men and women from the royal house of Avis, the most important sailors from this era, priests, knights, fishermen, navigators and beggars can be recognized in the picture.
Whoever the artist may ultimately prove to be, it is thought that he studied in Flanders. Although the stylistic originality of the work stands out it cannot actually be attributed to a particular European school. In contrast with the general custom of that time, the people have not been positioned in front of a background of countryside or architecture but stand alone. In this way concentration is completely directed on the serious faces and individual expressions of those portrayed.
Of the six large panels the two middle ones stand out. While all the people are only portrayed once, St Vincent appears on both the middle screens. His central position on these main screens underlines the importance the artist placed on Portugal's patron saint. As the two depictions of St Vincent are turned towards the center it is thought that there was eventually meant to be a seventh screen. This is allegedly contradicted by the lines of the ground which provide the only spatial clue; apart from that it is not known with certainty how the panels were hung, one above another, one below another on one next to another.
Particularly important people can be recognized in the left hand panel. Members of the family of King Afonso V surround St Vincent. Below on the right kneels Afonso V himself, behind him on the edge of the picture stands his son Joao, the later Joao II. Without doubt the most well known is the portrayal of Henry the Navigator (see Famous People), who was an uncle of Afonso V. On the left next to St Vincent kneels the wife of Afonso V, Queen Isabel, behind her stands Isabel of Aragón, a sister of Henry the Navigator and thus the king's aunt. In the background real people are also portrayed, although controversy reigns over their actual identities. Both the person on the very left and in the second panel on the left are thought to be self portraits of the altarpiece's supposed creator. Others maintain that Nuno Gonçalves immortalized himself on the right of the middle panels as the second person on the right in the row in the background.
On this second main panel priests and knights are gathered around St Vincent. Below on the left is Prince Fernao, Afonso V's brother and father of Manuel I. Archbishop Jaime of Lisbon can be recognized by his mitre. Clearly identifiable is the historian Gomes Eanes de Azurara on the top right, who dedicated himself in a chronicle to Henry the Navigator. The smaller outer panel on the right shows the second duke of Bragança, Fernao, and a Moorish knight. On the three remaining smaller side panels Cistercian monks from the Alcobaça monastery, fishermen and navigators can be seen. On the panel on the extreme right a beggar, a Jewish scholar with the Torah and a priest with the remains of St Vincent are depicted (chronological authenticity was apparently not adhered to).