Acayucan (160 m (525 ft)); population: 37,000), about 80km/58mi south-east of Catemaco on the MEX 180, is a major road junction where the MEX 185 branches off southwards, crossing the Isthmus of Tehuantepec to Juchitán (195km/121mi), Tehuantepec (220km/137mi; see entry) and Santa Cruz (235km/146mi).

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